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The Left Side is the superior choice for this route primarily due to the spectacular approach into the Valley of Mexico, which frequently provides unparalleled views of the iconic Popocatépetl and Iztaccíhuatl volcanoes.

The left side provides the most dramatic views of the Sierra Madre Occidental's complex canyon systems and the steep descent into the desert lowlands.

The left side offers a premier view of the high desert landscapes and the majestic canyons of Big Bend National Park, which is the undeniable highlight of this trans-border route.

The right side provides a front-row seat to the dramatic Sierra Madre Occidental mountain range and the iconic volcanic topography surrounding the Guadalajara valley.

The right side offers the most iconic views of the Samalayuca sand dunes and the dramatic approach into the binational Juarez-El Paso metropolitan area.

The right side offers a superior view of the dramatic Sierra Madre Oriental mountain range and the world-famous Cerro de la Silla during the approach into Monterrey.

The left side offers superior natural beauty, featuring the deep ravines of the Sierra Madre Occidental and the striking blue contrast of the Gulf of California.

The right side offers a superior mix of geographical transitions, including the dramatic peaks of the Sierra Madre Oriental, the lush tropical coastline of the Gulf, and the iconic turquoise waters of the Riviera Maya upon approach.

The right side provides a superior view of the dramatic Chihuahuan mountain ranges and the winding Rio Grande border, often concluding with views of the Dallas skyline during the arrival sequence.

The right side offers a superior view of the dramatic transition between the high plateau and the eastern foothills of the Sierra Madre Occidental, including the massive Boquilla Dam reservoir.